NCT02222636

The Clinical Research of Intranasal Dexmedetomidine Used in Plastic Surgery of Children

The Clinical Research of Intranasal Dexmedetomidine Used in Plastic Surgery of Children : A Single Center ,Randomized ,Double-blinded, Controlled Study.

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Xijing Hospital · Academic / Other
• Sex: All
• Age: 6 Months – 7 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to explore the optimal protocol for dexmedetomidine used in children during perioperative period.

Conditions

• The Efficacy and Safety of Intranasal Dexmedetomidine

Interventions

Type	Name	Description
DRUG	Normal saline,1 milliliter	Normal saline,1 milliliter, 20 minutes before anaesthetic induction
DRUG	Dexmedetomidine 1 μg.kg-1,1 milliliter	Dexmedetomidine 1 μg.kg-1,1 milliliter,20 minutes before anesthesia induction
DRUG	Dexmedetomidine 2μg.kg-1,1 milliliter	Dexmedetomidine 2μg.kg-1,1 milliliter,20 minutes before anesthesia induction
DRUG	Anesthesia induction, 8% sevoflurane	Inhalation induction with 8% sevoflurane
DRUG	Anesthesia maintenance, 2%~3% sevoflurane,fentanyl	2%\~3% sevoflurane,inhalation. fentanyl,2μg.kg-1.min-1,intravenous infusion

Timeline

• Start date: 2014-09-01
• Primary completion: 2015-08-01
• Completion: 2015-12-01
• First posted: 2014-08-21
• Last updated: 2014-08-21