Trials / Completed
CompletedNCT02220023
Dynamic Assessment of Right Ventricular Function With Inhaled Nitric Oxide During Cardiac MRI
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 17 (actual)
- Sponsor
- Vanderbilt University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study is to measure RV ejection fraction (RVEF), pulmonary flow, and pulmonary perfusion before and after exposure to inhaled nitric oxide in patients with pulmonary arterial hypertension (PAH) who are known to be vasodilator-responsive based on invasive catheterization as well as healthy subjects. Measurements will also be made after high flow oxygen alone to test the relative vasodilatory effect of oxygen and NO. The investigators hypothesize is that inhaled nitric oxide during cardiac MRI can be used to measure dynamic changes in RV-pulmonary vascular function in patients with vasodilator-responsive PAH.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | INOmax Inhalation |
Timeline
- Start date
- 2014-07-01
- Primary completion
- 2017-02-01
- Completion
- 2017-02-01
- First posted
- 2014-08-19
- Last updated
- 2017-02-13
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02220023. Inclusion in this directory is not an endorsement.