NCT02219061

Early Waning of Maternal Measles and Meningitis C Antibodies

Observation Study on Early Waning of Maternal Measles and Meningitis C Antibodies

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Guangzhou Center for Disease Control and Prevention · Other Government
• Sex: All
• Age: 7 Months
• Healthy volunteers: Accepted

Summary

Maternal antibodies (measles and meningitis C) may wane in the first six months after birth. * Geometric mean titers(GMTs) of measles and meningitis C. * Follow-up on 0 month, 3rd month,5th month and 7th month after birth.

Detailed description

Measles and meningitis C are hot topics in China in recent years. Although China had set the goal of measles elimination, many measles cases were found to be those aged \< 8 months and meningitis C is becoming public health issue since meningitis group A has been controlled at a very low level and little is known on C group. So the investigators designed the observation study on the two antibodies. Maternal antibodies are supposed to wane after birth. Serums of the placenta(0 month), children of 3 months, 5 months and 7 months old will be collected and the geometric mean titers (GMTs) of measles and meningitis C will be confirmed by using the ELISA test.

Conditions

• Measles

Timeline

• Start date: 2014-05-01
• Primary completion: 2014-10-01
• Completion: 2014-12-01
• First posted: 2014-08-18
• Last updated: 2014-09-18

Locations

1 site across 1 country: China