NCT02217267

Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain

Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain : A Pilot Study

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study to evaluated Long term outcome after serial Lidocaine infusion when compared with placebo in peripheral neuropathic pain patients in acute stage (less than 6 months) at 3 months after first time of infusion

Detailed description

Peripheral nerve injury may give rise to severe and long-lasting types of pains which are often resistant to treatment such as opioid, tricyclic antidepressant or anticonvulsant. Lidocaine infusion has been the one of intractable neuropathic pain treatment . My hypothesis the serial lidocaine infusion can adequate pain control and can prevent chronic pain (central sensitisation). Therefore, we designed this prospective, randomised, double-blind, controlled study to evaluate the efficacy of serial lidocaine infusion in peripheral neuropathic pain compared with placebo in long term outcome (at 3 month).

Conditions

• Peripheral Neuropathy

Interventions

Type	Name	Description
DRUG	Lidocaine	Lidocaine 3 mg/kg dilute in Normal Saline to 50 ml intravenous infusion in 1 hour
DRUG	Placebo

Timeline

• Start date: 2014-08-01
• Primary completion: 2017-12-29
• Completion: 2018-02-01
• First posted: 2014-08-15
• Last updated: 2022-11-30

Locations

1 site across 1 country: Thailand