Clinical Trials Directory

Trials / Unknown

UnknownNCT02213861

Efficacy, Safety and Tolerability Study of SHAPE in IA, IB or IIA Cutaneous T-cell Lymphoma

A Randomized Phase 2 Study to Evaluate Three Treatment Regimens of SHAPE, a Histone Deacetylase Inhibitor, in Patients With Stage IA, IB or IIA Cutaneous T-Cell Lymphoma

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
60 (estimated)
Sponsor
TetraLogic Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy, safety and tolerability of SHAPE administered topically to skin lesions in patients with early-stage cutaneous T-cell lymphoma (CTCL).

Detailed description

This is a Phase 2, multicenter, open-label, randomized study to evaluate the efficacy and safety of SHAPE Gelled Solution applied topically daily or twice daily for 26 consecutive weeks to specified skin lesions in patients with Stage IA, IB or IIA CTCL. Patients responding to treatment will be allowed to continue on study for a maximum of 52 weeks.

Conditions

Interventions

TypeNameDescription
DRUGSHAPEtopical gel

Timeline

Start date
2014-11-01
Primary completion
2016-10-01
Completion
2016-10-01
First posted
2014-08-12
Last updated
2016-10-20

Locations

5 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02213861. Inclusion in this directory is not an endorsement.