NCT02211391

Nighttime Protein Intake on Overnight Lipolysis and Morning Fat Oxidation in Obese Men

The Effect of Nighttime Protein Intake on Overnight Lipolysis and Morning Fat Oxidation in Obese Men.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Florida State University · Academic / Other
• Sex: Male
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Single macronutrients will be consumed before sleep by obese men. Overnight lipolysis will be measured with the microdialysis technique by measuring glycerol concentration and blood flow in abdominal adipose tissue. Morning fat oxidation will be measured with indirect calorimetry. The investigators hypothesize that carbohydrate intake will blunt the overnight lipolysis rate compared to casein protein and a non-caloric placebo. The investigators also hypothesize that casein and placebo will not be significantly different from each other in terms of overnight lipolysis.

Conditions

• Obesity

Interventions

Type	Name	Description
OTHER	Casein Protein	The effect of casein protein consumed within 30 minutes of sleep on overnight lipolysis and next morning metabolism and appetite will be examined
OTHER	Non-caloric placebo	The effect of a non-caloric placebo consumed within 30 minutes of sleep on overnight lipolysis and next morning metabolism and appetite will be examined

Timeline

• Start date: 2014-07-01
• Primary completion: 2015-08-01
• Completion: 2015-08-01
• First posted: 2014-08-07
• Last updated: 2015-08-13

Locations

1 site across 1 country: United States