NCT02207491

Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

A Double-masked, Randomized, Multi-center, Active-controlled, Parallel, 3-month Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-13324 Ophthalmic Solution, 0.02% Compared to Timolol Maleate Ophthalmic Solution, 0.5% in Patients With Elevated Intraocular Pressure

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 411 (actual)
• Sponsor: Aerie Pharmaceuticals · Industry
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

To evaluate the ocular hypotensive efficacy and ocular and systemic safety of AR-13324 Ophthalmic Solution, 0.02% compared to the active comparator Timolol maleate Ophthalmic Solution, 0.5%

Conditions

• Ocular Hypertension
• Open-angle Glaucoma

Interventions

Type	Name	Description
DRUG	Timolol maleate Ophthalmic Solution 0.5% BID	1 drop BID, AM/PM, OU
DRUG	AR-13324 Ophthalmic Solution 0.02%	1 drop once daily (QD), PM, OU
OTHER	Placebo	1 drop QD, AM, OU

Timeline

• Start date: 2014-07-01
• Primary completion: 2015-03-01
• Completion: 2015-03-01
• First posted: 2014-08-04
• Last updated: 2018-04-13
• Results posted: 2018-04-13

Locations

1 site across 1 country: United States