NCT02203812

Effect of Probiotic Lozenge on Gingivitis and Periodontitis

The Effect of Probiotic Lozenge Administration on Gingivitis and on Mild & Moderate Periodontitis: A Randomized Controlled Clinical Trial.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: CD Pharma India Pvt. Ltd. · Industry
• Sex: All
• Age: 20 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The oral cavity is mostly influenced by general health. The oral microbiota which is as complex as the gastro-intestinal or vaginal microbiota are considered to be difficult therapeutic targets. The effects of probiotics in different fields of health care have resulted recently in the introduction of probiotics for oral healthcare. Probiotics have been clinically proved effective in different fields of oral healthcare such as halitosis, oral candidiasis and tooth decay. They have also been inducted in the field of periodontal healthcare because of the current views on the etiology of plaque- related periodontal inflammation.

Conditions

• Mild and Moderate Chronic Periodontitis

Interventions

Type	Name	Description
DRUG	Probiotic Arm	Each Inersan lozenge contains at least 1 billion colony forming unit of Lactobacillus brevis CD2
DRUG	Placebo Arm	Placebo lozenges contain all ingredients except the active constituent (probiotic, Lactobacillus brevis CD2)

Timeline

• Start date: 2015-01-01
• Primary completion: 2016-02-01
• Completion: 2016-05-01
• First posted: 2014-07-30
• Last updated: 2016-07-27

Locations

1 site across 1 country: India