Trials / Completed
CompletedNCT02202564
Preliminary Results for the Double-dose Adenovirus-mediated Adjuvant Therapy Improving Outcome of Liver Transplantation in Patients With Advanced Hepatocellular Carcinoma
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 81 (actual)
- Sponsor
- Huazhong University of Science and Technology · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
HCC patients with tumors \>5 cm in diameter, regardless of involvement in the intrahepatic and extrahepatic portal branches participated in the study. Patients were randomized allocated in liver transplantation (LT) only group and LT plus ADV-TK therapy group. All patients received orthotopic liver transplantation; in the LT plus ADV-TK group, ADV-TK therapy was delivered to patients twice.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | LT | Orthotopic LT |
| DRUG | ADV-TK | |
| DRUG | ganciclovir |
Timeline
- Start date
- 2006-10-01
- Primary completion
- 2011-10-01
- Completion
- 2013-08-01
- First posted
- 2014-07-29
- Last updated
- 2014-07-29
Source: ClinicalTrials.gov record NCT02202564. Inclusion in this directory is not an endorsement.