NCT02201121

Influences of Phenylephrine, Dopamine and Ephedrine on Stroke Volume Variation and Pulse Pressure Variation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 94 (actual)
• Sponsor: Chinese PLA General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Although induced hypertension decreased SVV and PPV,the influences of stroke volume variation and pulse pressure variation caused by phenylephrine,dopamine and ephedrine were unknown.

Detailed description

Pulse pressure variation (PPV) and stroke volume variation (SVV) during mechanical ventilation have been shown to be effective parameters to predict preload responsiveness. Although induced hypertension decreases PPV and SVV, the influences of phenylephrine, dopamine and ephedrine on PPV and SVV are unknown.

Conditions

• Circulation
• Drug Dose
• Calculated SAP

Interventions

Type	Name	Description
OTHER	Influences of phenylephrine, dopamine and ephedrine on stroke volume variation and pulse pressure variation	This research mainly study the effect of clinical commonly used vasoconstrictor drugs on blood pressure of pressure

Timeline

• Start date: 2014-03-01
• Primary completion: 2014-06-01
• Completion: 2014-06-01
• First posted: 2014-07-25
• Last updated: 2014-07-25