NCT02199522

Clinical Observation of Titration Induction and Convention Induction of Propofol

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (actual)
• Sponsor: Lihong Chen · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

As we know propofol is popular use in the anesthesia induction with kilogram and it always cause hypotension. So we compare haemodynamic changes and drug consumption between propofol titrated administration and traditional administration for anesthesia induction.

Detailed description

GroupⅠreceived propofol 2 mg/kg intravenously by Fresenius pump at the speed of 250 mg/min, GroupⅡreceived propofol intravenously by Fresenius pump at the speed of 1 mg/kg/min, and observe's assessment of alertness and sedation(OAA/S) scale of the patients was titrated to 1, then changed to a maintenance dose

Conditions

• Propofol Overdose of Undetermined Intent

Interventions

Type	Name	Description
PROCEDURE	titration induction to propofol	propofol intravenously by Fresenius pump at the speed of 1 mg•kg-1•min-1, and OAA/S scale of the patients was titrated to 1

Timeline

• Start date: 2014-07-28
• Primary completion: 2014-11-30
• Completion: 2014-11-30
• First posted: 2014-07-24
• Last updated: 2020-10-22

Locations

1 site across 1 country: China