NCT02199418

Addition of Cisplatin to Neoadjuvant Therapy for T Locally Advanced Breast Cancer

Phase 2 Study of Weekly Paclitaxel in Combination With Cisplatin as Neoadjuvant Therapy for Locally Advanced Breast Cancer Patients

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 132 (actual)
• Sponsor: RenJi Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The investigators hypotheses that paclitaxel combined with cisplatin in a weekly-based regimen as neoadjuvant chemotherapy is effective and tolerable for locally advanced breast cancer.

Detailed description

In this trial, all the patients will have weekly paclitaxel and cisplatin as neoadjuvant chemotherapy for 4 cycles. Patients with Her2 positive tumor will also receive the trastuzumab.

Conditions

• Tubular Breast Cancer
• Mucinous Breast Cancer
• Invasive Ductal Breast Cancer
• Inflammatory Breast Cancer

Interventions

Type	Name	Description
DRUG	Paclitaxel
DRUG	Cisplatin

Timeline

• Start date: 2013-01-01
• Primary completion: 2015-11-01
• Completion: 2016-10-01
• First posted: 2014-07-24
• Last updated: 2017-01-25

Locations

2 sites across 1 country: China