Trials / Completed
CompletedNCT02193373
Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System
What is the Best Osteopathic Manipulative Medicine (OMM) Approach to Affect Autonomic Nervous System (ANS) Control of Heart Rate Variability (HRV)?
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 126 (actual)
- Sponsor
- New York Institute of Technology · Academic / Other
- Sex
- All
- Age
- 20 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The purpose this study is to determine which manual medicine technique or combination of techniques has the greatest effect on the natural changes in heart rate.
Detailed description
This study intends to examine how three different OMM techniques, sub-occipital release, rib-raising, and stellate ganglion release, impact autonomic nervous system tone. Subjects will be randomly assigned to one of four cohort groups, receiving either sub-occipital release, rib-raising, stellate ganglion release or all three treatment techniques. A shift towards sympathetic tone will be induced in all subjects using a tilted-to-seated-position test (Tilt-Seated Position test) and cognitive challenge test, consisting of computerized questions that become progressively more difficult, and which subjects are asked to answer as quickly and accurately as possible. These stress tests will be induced twice, once without any OMM treatment and a second time with the designated OMM treatment(s). The sympathetic-dependent response to orthostatic change and cognitive challenges will be determined by Fourier analysis of heart rate variability, recorded using an EKG attached to each subject.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Osteopathic Manual Medicine | Osteopathic Manual Medicine |
| OTHER | Sham | Osteopathic Manual Medicine |
Timeline
- Start date
- 2014-06-01
- Primary completion
- 2018-05-01
- Completion
- 2018-05-01
- First posted
- 2014-07-17
- Last updated
- 2019-07-05
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02193373. Inclusion in this directory is not an endorsement.