NCT02192996

Probiotic Supplementation to Improve the GUT Microbiota of Very Low Birth Weight Preterm, a Pilot Study

Probiotic Supplementation to Improve the GUT Microbiota of Very Low Birth Weight, a Pilot Study

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: Hospital Universitario La Paz · Academic / Other
• Sex: All
• Age: 1 Hour – 1 Week
• Healthy volunteers: Not accepted

Summary

This pilot trial is designed to investigate the benefits of the use of probiotics in GUT microbiota development and/or immunological biomarkers and how this can be related with the clinical status of very low birth weight preterms during their first weeks of life at the neonatal intensive care unit(NICU).

Detailed description

This pilot trial is designed to investigate the benefits of the use of mixtures of probiotics isolated from human milk in GUT microbiota development and/or immunological biomarkers. Furthermore, the relationship between evaluated parameters and the clinical status of very low birth weight preterms during their first weeks of life at the NICU will be analysed.

Conditions

• Other Preterm Infants
• NEC

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic	blood and fecal samples were collected from five VLBW preterms which were supplemented with a probiotic mixture of Bifidobacterium breve / Lactobacillus salivarius isolated from human milk

Timeline

• Start date: 2012-12-01
• Primary completion: 2013-02-01
• Completion: 2014-07-01
• First posted: 2014-07-17
• Last updated: 2014-07-17

Locations

1 site across 1 country: Spain