NCT02191488

ALA-induced PpIX Fluorescence During Brain Tumor Resection

Quantification of ALA-induced PpIX Fluorescence During Brain Tumor Resection

• Status: Active Not Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 540 (estimated)
• Sponsor: David W. Roberts · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

Removing a tumor from a patients brain is hard to do because, very often, brain tumors do not have boundaries that are easy for the patients surgeon to find. In many cases, the surgeon can't tell exactly where the tumor begins or ends. The surgeon usually can remove most of the patient's tumor by looking at the MRI images that were taken of the patient's brain before surgery. However, the surgeon does not have any good way to tell if the entire tumor has been removed or not. Removing the entire tumor is very important because leaving tumor behind may allow it to grow back which could decrease the chances of survival.

Conditions

• Brain Tumors

Interventions

Type	Name	Description
DRUG	5-aminolevulinic acid

Timeline

• Start date: 2014-07-01
• Primary completion: 2025-12-31
• Completion: 2026-12-31
• First posted: 2014-07-16
• Last updated: 2025-09-15

Locations

1 site across 1 country: United States