Clinical Trials Directory

Trials / Completed

CompletedNCT02188277

Treatment With Xeomin Versus Botox in Children With Spastic Equine and Equinovarus Foot Deformation in Pediatric Cerebral Palsy

Multi-center Open Comparative Randomized Trial of Clinical and Neurophysiological Efficacy and Safety of Xeomin (Botulinum Toxin Type A) vs. Botox (Complex of Botulinum Toxin Type A and Hemagglutinin) in Children With Spastic Equine and Equinovarus Foot Deformation in Pediatric Cerebral Palsy

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
64 (actual)
Sponsor
Merz Pharmaceuticals GmbH · Industry
Sex
All
Age
2 Years – 12 Years
Healthy volunteers
Not accepted

Summary

1. To assess the clinical and neurophysiological efficacy of Xeomin® vs. Botox® in children with spastic equine and equinovarus foot deformation in pediatric cerebral palsy 2. To assess the safety of Xeomin® use as compared to Botox® in this patient population

Conditions

Interventions

TypeNameDescription
DRUGXeominActive ingredient: Clostridium Botulinum neurotoxin Type A free from complexing proteins. Solution for injection prepared by reconstitution of powder with 0.9% Sodium Chloride (NaCl). Administration route is intramuscular injection into medial (two points) and lateral heads (two points) of gastrocnemius.
DRUGBotox®Administration route is intramuscular injection into medial (two points) and lateral heads (two points) of gastrocnemius.

Timeline

Start date
2014-07-01
Primary completion
2016-12-01
Completion
2016-12-01
First posted
2014-07-11
Last updated
2017-01-26

Locations

3 sites across 1 country: Russia

Source: ClinicalTrials.gov record NCT02188277. Inclusion in this directory is not an endorsement.