NCT02185339

Effects of Deep Neuromuscular Blockade on Intraoperative Respiratory Mechanics

Effects of Deep Versus Moderate Neuromuscular Blockade on Intraoperative Respiratory Mechanics in Patients Undergoing Laparoscopic Renal Surgery: a Prospective, Randomized, Parallel Design Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: Seoul St. Mary's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of the current study is to compare intraoperative respiratory mechanics in patients receiving laparoscopic renal surgery under deep neuromuscular blockade (dNMB) and under moderate neuromuscular blockade (mNMB). In addition, we will compare intraoperative hemodynamics and postoperative pulmonary function between the two groups.

Conditions

• Laparoscopic Renal Surgery
• Laparoscopy
• Muscle Relaxation

Interventions

Type	Name	Description
DRUG	Rocuronium	Intravenous infusion rate of rocuronium will be titrated to keep post-tetanic count between 1 to 2.
DRUG	Rocuronium	Intravenous infusion rate of rocuronium will be titrated to keep train-of-four count between 1 to 2.

Timeline

• Start date: 2014-07-01
• Primary completion: 2015-01-01
• Completion: 2015-01-01
• First posted: 2014-07-09
• Last updated: 2016-07-25
• Results posted: 2016-06-24

Locations

1 site across 1 country: South Korea