Trials / Withdrawn

WithdrawnNCT02183896

Efficacy of PRP (Platelet Rich Plasma) Following Arthroscopic Microfracture of Chondral Lesions of the Hip

Status: Withdrawn
Phase: N/A
Study type: Interventional
Enrollment: 0 (actual)

Sponsor: University of Colorado, Denver · Academic / Other
Sex: All
Age: 18 Years – 50 Years
Healthy volunteers: Not accepted

Summary

Detailed description

The purpose of this research project is to assess the effectiveness of intra-articular injections of autologous platelet-rich plasma (PRP) after arthroscopic microfracture. Our hypothesis is that platelet-rich plasma will improve patient's clinical outcomes and chondral healing following microfracture performed during femoroacetabular impingement (FAI) hip arthroscopy. This study has two aims: 1. Evaluate clinical efficacy of intra-articular injections of platelet-rich plasma (PRP) following arthroscopic microfracture. 2. Evaluate if microfracture followed by PRP injections improves chondral healing. Microfracture has shown good results with chondral lesions of the hip. However, microfracture does not regenerate normal hyaline cartilage. There is growing evidence that PRP can improve articular cartilage healing. Injection of PRP following microfracture may help regeneration to normal hyaline like articular cartilage together with soft tissue healing, thereby improving patients' early and long-term outcomes of chondral healing. Patients will be randomized to one of two study arms - microfracture with PRP (treatment arm) and microfracture with saline (control arm) in a 1:1 ratio.

Conditions

Interventions

Type	Name	Description
BIOLOGICAL	Platelet-rich plasma (PRP)
DRUG	Saline

Timeline

Start date: 2014-07-01
Primary completion: 2015-07-01
Completion: 2015-07-01
First posted: 2014-07-08
Last updated: 2018-12-28

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02183896. Inclusion in this directory is not an endorsement.