Clinical Trials Directory

Trials / Completed

CompletedNCT02183376

Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects

Pharmacokinetics and Pharmacodynamics of BI 1356 5 mg Once Daily in Male and Female Subjects With Different Degrees of Liver Impairment (Child Pugh Classification A-C) as Compared to Male and Female Healthy Subjects (a Non-blinded, Parallel Group Study of Phase I)

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
33 (actual)
Sponsor
Boehringer Ingelheim · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Accepted

Summary

To investigate the influence of mild, moderate, and severe liver impairment on the pharmacokinetics and pharmacodynamics of linagliptin in comparison with a control group with normal hepatic function after single or multiple oral administration of 5 mg linagliptin tablets

Conditions

Interventions

TypeNameDescription
DRUGBI 1356

Timeline

Start date
2008-07-01
Primary completion
2009-03-01
First posted
2014-07-08
Last updated
2014-07-08

Source: ClinicalTrials.gov record NCT02183376. Inclusion in this directory is not an endorsement.