Clinical Trials Directory

Trials / Completed

CompletedNCT02181764

A Study of KRN23 in Subjects With X-linked Hypophosphatemic Rickets/Osteomalacia

A Phase 1, Multicenter, Open-label, Sequential Dose-escalation, Single-dose Study to Assess the Safety and Tolerability of KRN23 in Subjects With X-linked Hypophosphatemic Rickets/Osteomalacia.

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
15 (actual)
Sponsor
Kyowa Kirin Co., Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The objective of this study is to assess the safety and tolerability of KRN23 after a single subcutaneous (SC) administration in subjects with X-linked hypophosphatemic rickets/osteomalacia (XLH) in Japan or Korea.

Conditions

Interventions

TypeNameDescription
DRUGKRN23Single SC administration on day 1: 0.3, 0.6 and 1.0 mg/kg

Timeline

Start date
2014-07-01
Primary completion
2015-06-01
Completion
2015-06-01
First posted
2014-07-04
Last updated
2017-03-03

Locations

2 sites across 2 countries: Japan, South Korea

Source: ClinicalTrials.gov record NCT02181764. Inclusion in this directory is not an endorsement.