NCT02179034

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 59 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years – 20 Years
• Healthy volunteers: Accepted

Summary

This study is to examine if inhaled doses of menthol that produce low and high cooling effects change the appeal of e-cigarettes containing low and high doses of nicotine in adolescent smokers. The hypothesis is that the combination of nicotine and menthol, when compared with menthol or nicotine alone, will result in greater increase in liking of an e-cigarette and greater reduction in nicotine withdrawal.

Conditions

• Nicotine Dependence, Other Tobacco Product

Interventions

Type	Name	Description
DRUG	Nicotine	Participants will receive no nicotine, low dose nicotine (6 mg/ml) or high dose nicotine (12 mg/ml)
OTHER	Low Dose Menthol	A low dose of menthol will be added to the tobacco flavor.
OTHER	High Dose Menthol	A high dose of menthol will be added to the tobacco flavor.

Timeline

• Start date: 2014-10-23
• Primary completion: 2016-07-18
• Completion: 2017-06-12
• First posted: 2014-07-01
• Last updated: 2020-05-04

Locations

1 site across 1 country: United States