Clinical Trials Directory

Trials / Terminated

TerminatedNCT02175654

Regorafenib as Single Agent in Patients With Metastatic Colorectal Cancer (mCRC) With Any RAS or BRAF Mutation Previously Treated With FOLFOXIRI Plus Bevacizumab

Phase II Study of Regorafenib as Single Agent for the Treatment of Patients With Metastatic Colorectal Cancer (mCRC) With Any RAS or BRAF Mutation Previously Treated With FOLFOXIRI Plus Bevacizumab

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
15 (actual)
Sponsor
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess the efficacy of single-agent regorafenib in the second-line treatment in metastatic colorectal cancer with any RAS or BRAF mutation previously treated with FOLFOXIRI plus bevacizumab in terms of progression-free survival at 6 months.

Conditions

Interventions

TypeNameDescription
DRUGRegorafenib

Timeline

Start date
2014-06-01
Primary completion
2016-02-01
Completion
2016-02-01
First posted
2014-06-26
Last updated
2017-08-01

Locations

1 site across 1 country: Spain

Source: ClinicalTrials.gov record NCT02175654. Inclusion in this directory is not an endorsement.