NCT02173613

Reduction the Duration of Antibiotic Therapy in the Elderly (PROPAGE)

Reduction of the Duration of Antibiotic Guided by Procalcitonin in Infections Lungs of Hospitalized Elderly: a Randomized

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 117 (actual)
• Sponsor: University Hospital, Grenoble · Academic / Other
• Sex: All
• Age: 80 Years
• Healthy volunteers: Not accepted

Summary

The main objective is to evaluate the interest of the repeated measurement of procalcitonin in patients with pulmonary infection to reduce the duration of antibiotic therapy in comparison with a conventional clinical strategy.

Conditions

• Lung Infection

Interventions

Type	Name	Description
OTHER	procalcitonine	The recommendations will be based on the level of PCT: 4 levels of advice will be given: * It is highly recommended to stop antibiotics if PCT \<0.1ng/ml, and the recommended stop if 0.1ng/ml \<PCT \<0.25 ng / ml. * It is recommended to continue treatment if 0.25 ng / ml \<PCT ng / ml. * Finally, if the initial PCT greater than 10 ng / ml, a stop will be advised in case of reduction to less than 10% of baseline level.

Timeline

• Start date: 2012-08-01
• Primary completion: 2015-12-01
• Completion: 2016-03-01
• First posted: 2014-06-25
• Last updated: 2022-05-02

Locations

1 site across 1 country: France