Clinical Trials Directory

Trials / Completed

CompletedNCT02172677

The Influence of Collective Schemas on Individual Memory (MULTIBRAIN_1)

ETUDE D'IMAGERIE PAR RESONANCE MAGNETIQUE FONCTIONNELLE CHEZ LE SUJET SAIN DES RELATIONS ENTRE MEMOIRE COLLECTIVE ET INDIVIDUELLE

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
27 (actual)
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France · Other Government
Sex
All
Age
20 Years – 38 Years
Healthy volunteers
Accepted

Summary

Schemas describe mental structures storing recurrent and organized pattern of information. Schemas may have a strong influence on the process of storing and retrieving new information into memory. Previous approaches in the cognitive neuroscience of memory have entirely focused on the individual dimension of preexisting schemas. In the real world though, much of our experiences and knowledge are collective or shared. Such social-cultural frameworks stored in collective memory may also reshape and reconfigure the construction of individual memories. Attempting to ascertain the influence of collective schema on the neural substrates of individual memories using cutting-edge brain imaging methods represents the challenge that MULTIBRAIN seeks to tackle. To achieve this goal, we will record brain activity in a group of 24 participants while there are remembering pictures from a tour at the World War II Memorial of Caen. This study will seek to identify brain areas of the prefrontal cortex encoding the organization of knowledge in collective memory using multivariate analyses of brain patterns of activation, and then to understand how such regions might modulate the recruitment of the hippocampus during episodic memory retrieval using analyses of effective connectivity. The organization of knowledge in collective memory is measured in parallel through 1) the analysis of French social memory of World War II using a corpus of 100 000 television and radio shows from the National Institute of Audiovisual, and 2) an internet task measuring the organization of individual knowledge in a large group of individuals that will allow to separate shared from non-shared memories of the World War II. Once collected, these data will help us to understand how collective schemas may reconfigure the organization of individual memories.

Conditions

Interventions

TypeNameDescription
BEHAVIORALEpisodic memory task
DEVICEfMRI

Timeline

Start date
2014-10-01
Primary completion
2016-10-14
Completion
2016-10-14
First posted
2014-06-24
Last updated
2025-09-04

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT02172677. Inclusion in this directory is not an endorsement.