NCT02169843

Small Doses of Dexmedetomidine for Emergence Agitation

Influence of Small Doses Dexmedetomidine to the Elderly Patients' Emergence Agitation

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Tang-Du Hospital · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

Dexmedetomidine Hydrochloride is a kind of high selectivity alpha 2 agonists adrenaline, can inhibit the activity of sympathetic nerve, and reduce the adverse effects of stress reaction in anesthesia recovery period.Literatures have been reported that Dex can reduce the rate of emergence agitation of children and adults,especially in elderly patients(\>64 years) after using sevoflurane anesthesia.

Conditions

• Emergence Agitation

Interventions

Type	Name	Description
DRUG	Sevoflurane	inhale Sevoflurane
DRUG	Dexmedetomidine	intravenous pumping Dexmedetomidine 0.2µg/kg/h
DRUG	Placebo(for Dexmedetomidine)	normal saline mimic Dexmedetomidine, intravenous pumping 0.05ml/kg/h

Timeline

• Start date: 2014-05-01
• Primary completion: 2014-10-01
• Completion: 2014-10-01
• First posted: 2014-06-23
• Last updated: 2014-06-23

Locations

1 site across 1 country: China