NCT02169141

Pharmacokinetics of Levofloxacin and Capreomycin in Multidrug-Resistant Tuberculosis Patients

Pharmacokinetics of Levofloxacin and Capreomycin in MDR-TB Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: University Medical Center Groningen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is an open label observational pharmacokinetic drug study to evaluate Levofloxacine and Capreomycin in patients with Multidrug-Resistant Tuberculosis (MDR-TB).

Detailed description

Patients receive MDR-TB treatment with o.a. Levofloxacin and Capreomycin. At least one week after start of treatment, the PK samples samples will be obtained via an intravenous catheter at 0, 1, 2, 3, 4, 7, and 12 hours after intake.

Conditions

• Tuberculosis

Interventions

Type	Name	Description
OTHER	Pharmacokinetics	multiple blood samples are obtained by means of an indwelling intravenous catheter for calculating PK parameters

Timeline

• Start date: 2012-11-01
• Primary completion: 2013-02-01
• Completion: 2013-11-01
• First posted: 2014-06-23
• Last updated: 2014-06-23

Locations

1 site across 1 country: Belarus