NCT02167334

Using Positive Pressure Ventilation for Preoxygenation During Panendoscopy.

Non Invasive Ventilation (NIV) Versus Spontaneous Breathing for Preoxygenation During Ear, Nose, and Throat (ENT) Panendoscopy. A Controlled, Prospective, Randomized Study.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

the aim of the study is to determine if Spontaneous Ventilation with Positive Pressure Ventilation (PPV) preoxygenation allows a longer non hypoxemic apnea time during panendoscopy compared to spontaneous breathing preoxygenation. the hypothesis is PPV extends the residual functional capacity of lung so it provides more oxygen during apnea.

Conditions

• ENT Cancer Screening

Interventions

Type	Name	Description
DEVICE	positive pressure ventilation	Positive Pressure Ventilation with a 4 cmH2O inhale pressure, a positive end-expiratory pressure of 4 cm H2O, a trigger 2, an inspiratory slope of 0, an inhaled oxygen fraction of 100% administered at a 10 L / min flow.
PROCEDURE	Oxygenation with simple breathing mask	Spontaneously breathing preoxygenation with adapted face mask, to restrict leakage, at 10L/min oxygen, with inhaled fraction of 100% and a 2 L balloon volume.

Timeline

• Start date: 2013-09-01
• Primary completion: 2013-09-01
• Completion: 2014-06-01
• First posted: 2014-06-19
• Last updated: 2025-09-22

Locations

1 site across 1 country: France