NCT02165657

Excimer Laser, Serum Markers & Psoriasis

Effects of UVB Excimer Laser on Serum Inflammatory Markers in Patients With Psoriasis

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University Hospitals Cleveland Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The overall aims for this study are to determine whether UVB excimer laser treatment of psoriasis affects serum inflammatory markers, and to assess hyperpigmentation and erythema with excimer laser treatment. The investigators hypothesize that treatment of psoriasis with UVB delivered via 308 nm excimer laser will decrease the levels of serum inflammatory markers. The investigators hypothesize that treatment will decrease plaque erythema and will result in minimal hyperpigmentation.

Detailed description

Subjects will undergo Excimer treatment twice a week until they reach a PASI 75 improvement, or until they reach the maximum of 20 total treatments. A blood draw to assess serum inflammatory markers will be performed at the screening visit and final visit. Chromameter assessment, photographs, PASI and PGA (Physician Global Assessment) will be performed throughout the study to monitor psoriasis improvement, hyperpigmentation and erythema.

Conditions

• Psoriasis

Interventions

Type	Name	Description
DEVICE	Excimer laser treatment	Excimer laser irradiation twice a week for up to 20 treatments.

Timeline

• Start date: 2013-09-01
• Primary completion: 2017-03-01
• Completion: 2017-03-01
• First posted: 2014-06-17
• Last updated: 2021-07-16

Locations

1 site across 1 country: United States