NCT02164071

Validation of a Comprehensive Health Status Assessment Scale in Elderly Patients (≥ 65 Years) With Hematological Malignancies

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 363 (actual)
• Sponsor: Celgene · Industry
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

The elderly comprise the most prevalent population in oncology practice. The available evidence suggests that old patients are undertreated patients, mainly because of their advanced age, regardless of whether they are highly functional patients, they do not present co morbidities and could benefit from oncology therapies. Treatment planning must consider several health indices that are useful when it comes to detecting geriatric problems that could affect the patient's treatment experience. The complete comprehensive geriatric evaluation stands out as cornerstone among other validated tools that do not work as isolated instruments; however, its length and complexity may hinder its routine use in clinical practice for decision making. The purpose of this study is to validate a comprehensive health status assessment scale in elderly patients (≥65 years) with hematological malignancies that, while integrating the essential dimensions of geriatric assessment and, with the same precision as the currently available valid tools, is shorter and easier to apply, so it can be incorporated into the daily practice and that aids in clinical decision making objectively. If so, this information would help identify patients that could benefit from a specific oncology treatment, thus contributing to developing a targeted intervention plan and to optimizing the cancer results in this patient population.

Conditions

• Myelodysplastic Syndromes
• Leukemia Myeloid Acute
• Multiple Myeloma
• Leuklemia, Lymphocytic, Chronic

Interventions

Type	Name	Description
OTHER	Geriatric Assessment of Health Status Scale administration	Scale will be administered to all patients (3 cohorts) at baseline and then after 5 and not more than 15 days

Timeline

• Start date: 2012-04-11
• Primary completion: 2013-12-03
• Completion: 2015-07-04
• First posted: 2014-06-16
• Last updated: 2019-11-18

Locations

22 sites across 1 country: Spain