NCT02161835

Relations Between Myotonia and Fitness

Relations Between Fitness Status and the Severity of Myotonia in Patients With Congenital Myotonia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: Grete Andersen, MD · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Investigators aimed to investigate whether training can increase fitness levels in patients with myotonia, and thereby reduce the symptom of myotonia.

Detailed description

Investigators aimed to investigate whether a 10-week bicycle exercise program can increase fitness levels in patients with myotonia, and thereby reduce the symptom of myotonia in everyday life. The effect on myotonia is assessed by a standardized myotonia scale with six statements concerning self-rated myotonia, and a number of performance tests that objectively describes the degree of myotonia. The effect of the training program is assessed by an incremental test, measuring maximal oxygen uptake, maximal heart rate and maximal workload. The muscle enzyme creatine kinase (CK) is measured in plasma to follow muscle injury and safety during the training.

Conditions

• Congenital Myotonia

Interventions

Type	Name	Description
OTHER	Training	30 minutes of home based pulse watch regulated cycle-ergometer exercise, three times a week at 75% of maximal oxygen consumption.

Timeline

• Start date: 2014-04-01
• Primary completion: 2015-02-01
• Completion: 2015-02-01
• First posted: 2014-06-12
• Last updated: 2015-05-14

Locations

1 site across 1 country: Denmark