Trials / Completed
CompletedNCT02161692
Conventional Dose Versus High Dose Sequential Chemotherapy for Poor Prognosis Germ Cell Tumors
Randomized Phase 2 Study of Conventional Dose Chemotherapy Versus High Dose Sequential Chemotherapy as First-line Therapy for Metastatic Poor Prognosis Germ Cell Tumors
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Academic / Other
- Sex
- Male
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine whether the use of a sequential high dose chemotherapy is more effective than conventional dose (i.e. 4 cycles of cisplatin, etoposide, and bleomycin \[PEB\]) in patients with metastatic poor prognosis germ cell tumors.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Cyclophosphamide | |
| DRUG | Etoposide | |
| DRUG | Cisplatin | |
| DRUG | Bleomycin | |
| DRUG | Carboplatin | High dose carboplatin |
Timeline
- Start date
- 1996-12-01
- Primary completion
- 2007-05-01
- Completion
- 2009-04-01
- First posted
- 2014-06-12
- Last updated
- 2014-06-12
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT02161692. Inclusion in this directory is not an endorsement.