NCT02161198

Efficacy and Safety Study of Ginseng Polysaccharide Extract

A Single-center, Randomized, Placebo-controlled, Double-blind Clinical Trial to Evaluate the Efficacy and Safety After 14-week of Ginseng Polysaccharide Extract

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: Seoul St. Mary's Hospital · Academic / Other
• Sex: All
• Age: 50 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Y-75/ginsan is an acidic polysaccharide with a molecular weight of 150,000 Da, isolated from the aqueous Korean Panax ginseng extract. Preclinical laboratory studies have shown its function as an immunomodulatory molecule. The present study performed to evaluate the safety and beneficial effects of Y-75 on immune function in a group of healthy adults. The focus of this trial was modulation of innate immunity, comprising cytotoxic activity of natural killer cells, phagocytic activity of polymorphonuclear leukocytes and mononuclear phagocytes, and serum levels of monocyte-derived mediators.

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Y-75	Y-75 (1 g) and starch (1 g) as a diluting agent and were packed to contain 2 g/package
DIETARY_SUPPLEMENT	Placebo	Caramel syrup (0.03 g) and starch (1.97 g) were packed identically to the active treatment

Timeline

• Start date: 2012-09-01
• Primary completion: 2013-04-01
• Completion: 2013-12-01
• First posted: 2014-06-11
• Last updated: 2014-06-11

Locations

1 site across 1 country: South Korea