NCT02155010

Dexmedetomidine in Spinal Anesthesia

Hemodynamic Effect of Dexmedetomidine on Heavy Bupivacaine Spinal Anesthesia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Inje University · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Patients were randomized into two groups, A group and B group. A group and B group patients are injected intravenous dexmedetomidine after intrathecal injection (IT) of heavy bupivacaine and injected intravenous dexmedetomidine before IT of heavy bupivacaine, respectively. The investigators will compare of hemodynamics and patient's comfortability between two groups.

Detailed description

A and B group patients will intravenous inject dexmedetomidine 1mcg/kg for 10 minute loading infusion and 0.2mcg/kg/hr for continuous infusion. A group receive intravenous dexmedetomidine after procedure, and B group receive intravenous dexmedetomidine before procedure. Both group patients will hydrate 6 ml/kg crystalloid solution and will evaluated patient's anxiety and comfortability perioperative period. Vital signs will record 5 minutes interval at operating room and post-anesthetic care units.

Conditions

• Blood Pressure
• Anxiety

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	Dexmedetomidine infusion before intrathecal injection of heavy bupivacaine
DRUG	Dexmedetomidine with heavy bupivacaine	Dexmedetomidine infusion after IT of heavy bupivacaine

Timeline

• Start date: 2014-03-01
• Primary completion: 2015-07-01
• Completion: 2015-07-01
• First posted: 2014-06-04
• Last updated: 2016-09-26
• Results posted: 2016-09-26

Locations

1 site across 1 country: South Korea