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Trials / Completed

CompletedNCT02154815

Pre-emptive Kidney Transplantation Quality of Life

Evaluation of the Benefits Associated With Pre-emptive Kidney Transplantation. Prospective, Multicenter and Controlled Study of Quality of Life, Psychological Adjustment Processes and Medical Outcomes of Patients Receiving a Pre-emptive Kidney Transplant Compared to a Similar Population of Recipients After a Dialysis Period of Less Than Three Years

Status
Completed
Phase
Study type
Observational
Enrollment
390 (actual)
Sponsor
Nantes University Hospital · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The main objective is to assess the psychological impact of pre-emptive kidney transplantation on patients' quality of life taking into account psychological adjustment (response shift), compared to patients who have experienced a short pre-transplant dialysis period of less than 36 months.

Detailed description

The following outcomes will also be compared between Patients with Pre-emptive Transplantation and Patients with Dialysis before Transplantation : a) changes in quality of life, subjective well-being, perceived anxiety and depressive disorders as well as perceived stress during follow-up taking into account psychological adjustment (response shift) ; b) The coping strategies (process of managing stressful circumstances) and post-traumatic growth (positive psychological change experienced as a result of the struggle with highly challenging life circumstances) ; c) The 2-year post transplantation graft survival and patient outcomes: evolution of the Graft Filtration Rate, the proteinuria level ; d) The Kidney Transplant Failure Score (KTFS, patent N°0959043) at one year post transplantation ; e) The post-transplantation time to return to work and patients compliance to treatment.

Conditions

Interventions

TypeNameDescription
OTHERQuestionnaires : Patient-Reported OutcomesPatient-Reported Outcomes completion every six months prior to surgery, at hospital discharge, and at 3, 6,12, 24, 36, 48, 72 months

Timeline

Start date
2014-09-01
Primary completion
2018-09-01
Completion
2024-07-25
First posted
2014-06-03
Last updated
2024-08-27

Locations

5 sites across 1 country: France

Source: ClinicalTrials.gov record NCT02154815. Inclusion in this directory is not an endorsement.

Pre-emptive Kidney Transplantation Quality of Life (NCT02154815) · Clinical Trials Directory