NCT02150759

Dexmedetomidine-ketamine in Femur Proximal Fracture Patients

Comparison Study of Analgesic Effects for Dexmedetomidine-fentanyl vs Dexmedetomidine-ketamine in Femur Proximal Fracture Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Inje University · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

* Comparison study of analgesic effects for dexmedetomidine-fentanyl vs dexmedetomidine-ketamine * lateral position for spinal anesthesia in femur proximal fracture patients

Detailed description

* Dexmedetomidine (1mcg/kg)- fentanyl (1mcg/kg) vs dexmedetomidine (1mcg/kg) - ketamine (1mg/kg) 10 minutes loading. * After 10 minutes of drug infusion, patients are prepared for spinal anesthesia. * pain scale and quality of patient positioning are measured three times (lateral position, chest-knee position, intrathecal local anesthetics injection) * When patients have severe pain during intraoperative period, fentanyl 50 mcg will be intravenously inject. * Patients will be injected propofol 10mg when they have agitation signs during operation. * vital signs, bispectral index, korean version of mini mental status examination, verbal rating scale,fentany/propofol consumption, frequency of intrathecal injection

Conditions

• Pain

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	dexmedetomidine infusion during spinal anesthesia
DRUG	Fentanyl	add dexmedetomidine during position change
DRUG	Ketamine	add dexmedetomidine during position change

Timeline

• Start date: 2014-05-01
• Primary completion: 2017-11-01
• Completion: 2017-11-01
• First posted: 2014-05-30
• Last updated: 2019-04-29
• Results posted: 2019-04-29

Locations

1 site across 1 country: South Korea