Trials / Completed
CompletedNCT02149927
Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Technical University of Munich · Academic / Other
- Sex
- Male
- Age
- 18 Years – 35 Years
- Healthy volunteers
- Accepted
Summary
In imaging functional connectivity (FC) analyses of the resting brain, alterations of FC during unconsciousness have been reported. These results are in accordance to recent electroencephalographic studies observing impaired top-down processing during anesthesia. In this study, simultaneous records of functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) were performed to investigate the causality of neural mechanisms during sevoflurane anesthesia by correlating FC in fMRI and directional connectivity (DC) in electroencephalogram.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Sevoflurane |
Timeline
- Start date
- 2013-06-01
- Primary completion
- 2013-12-01
- Completion
- 2014-01-01
- First posted
- 2014-05-29
- Last updated
- 2014-05-29
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT02149927. Inclusion in this directory is not an endorsement.