NCT02147769

Cerebral Oxygenation and Autoregulation in Preterm Infants

Cerebral Oxygenation and Autoregulation in Preterm Infants: Association With Morbidity and Mortality

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 111 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 24 Hours
• Healthy volunteers: Not accepted

Summary

Premature infants are at high risk for variations in blood pressure and oxygenation during the first few days of life. The immaturity of the premature brain may further predispose these infants to death or the development of neurologic problems. The relationship between unstable blood pressure and oxygen levels and brain injury has not been well elucidated. This study investigates the utility of near-infrared spectroscopy (NIRS), a non-invasive oxygen-measuring device, to identify preterm infants at highest risk for brain injury or death.

Conditions

• Intraventricular Hemorrhage of Prematurity
• Complications of Prematurity

Interventions

Type	Name	Description
DEVICE	NIRS monitoring	All enrolled infants will undergo NIRS monitoring of cerebral oxygenation in addition to monitoring of continuous arterial blood pressure.

Timeline

• Start date: 2014-05-01
• Primary completion: 2017-12-01
• Completion: 2018-03-01
• First posted: 2014-05-28
• Last updated: 2020-04-07
• Results posted: 2020-04-07

Locations

7 sites across 1 country: United States