Trials / Completed
CompletedNCT02147028
Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases
A Randomized Phase II Trial of Hippocampal Sparing Versus Conventional Whole Brain Radiotherapy After Surgical Resection or Radiosurgery in Favourable Prognosis Patients With 1-10 Brain Metastases
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 23 (actual)
- Sponsor
- University College, London · Academic / Other
- Sex
- All
- Age
- 16 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate whether sparing the hippocampi during whole brain radiotherapy following neurosurgery or stereotactic radiosurgery in patients with brain metastases from a systemic tumour helps preserve brain function.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | Hippocampal sparing whole brain radiotherapy | 30 Gy in 10 fractions hippocampal sparing whole brain radiotherapy will be administered by Helical Tomotherapy, IMRT, or VMAT |
| RADIATION | Conventional whole brain radiotherapy | 30 Gy in 10 fractions conventional whole brain radiotherapy will be administered |
Timeline
- Start date
- 2016-08-03
- Primary completion
- 2018-06-01
- Completion
- 2021-02-16
- First posted
- 2014-05-26
- Last updated
- 2021-02-25
Locations
7 sites across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT02147028. Inclusion in this directory is not an endorsement.