NCT02145416

ART: Anal Squamous Cell Carcinoma: Investigation of Functional Imaging During chemoRadioTherapy

Anal Squamous Cell Carcinoma: Investigation of Functional Imaging During chemoRadioTherapy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 29 (actual)
• Sponsor: University of Oxford · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a single arm, single centre imaging study which will be offered to all consecutive, eligible patients receiving radical chemoradiation therapy (CRT) for anal cancer within Oxford University Hospitals. Investigations * Dynamic contrast enhanced magnetic resonance imaging (DCE MRI) * Diffusion weighted magnetic resonance imaging (DWI MRI) * MRI scan designed to measure the T1 or produce T1-weighed images (T1 MRI) * MRI scan designed to measure the T2\* or produce T2\*-weighed images (T2\* MRI) * Perfusion computed tomography (pCT) * Fludeoxyglucose positron emission tomography (FDG PET/CT) Study Design: Observational Target Population: Patients undergoing radical CRT for anal cancer in Oxford University Hospitals National Health Service (NHS) Trust. Duration on study: Patients should be on study for a maximum of 5 months. Patient care post-trial: Follow up as per local standard. No. of Study Site(s): Single Centre, United Kingdon (UK) End of study: Last Patient, last assessment of response. Patients should be on study for a maximum of 5 months.

Conditions

• Anal Cancer

Timeline

• Start date: 2015-01-27
• Primary completion: 2017-12-08
• Completion: 2018-04-12
• First posted: 2014-05-22
• Last updated: 2018-06-06

Locations

1 site across 1 country: United Kingdom