NCT02140697

Efficacy and Safety of Hippophae Rhamnoides L. Leaf Extract on Body Fat

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Chonbuk National University Hospital · Academic / Other
• Sex: All
• Age: 19 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Obesity is a major health issue worldwide; there is a constant raise in obesity related death each year. In vitro and animal studies elucidated Hippophae rhamnoides L. Leaf Extract as a novel anti-obesity agent. However, the efficacy and safety of Hippophae rhamnoides L. Leaf Extract supplementation on body weight regulation in humans are lacking.

Detailed description

The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Hippophae rhamnoides L. Leaf Extract on body fat. The investigators measured Body Fat Mass, Percent Body Fat, Fat Free Mass, weight, and body mass index.

Conditions

• Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Hippophae rhamnoides L. Leaf Extract (3g/day)	Hippophae rhamnoides L. Leaf extract (3g/day), parallel design
DIETARY_SUPPLEMENT	Placebo (3g/day)	Placebo (3g/day), parallel design

Timeline

• Start date: 2014-05-01
• Primary completion: 2014-08-01
• Completion: 2014-12-01
• First posted: 2014-05-16
• Last updated: 2016-05-16

Locations

1 site across 1 country: South Korea