Trials / Completed
CompletedNCT02140593
The Laparotomy Study
Muscle Relaxation During Open Upper Abdominal Surgery - Can the Surgical Conditions be Optimized?
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 128 (actual)
- Sponsor
- Herlev Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The depth of neuromuscular blockade (NMB) during surgery may cause a clinical dilemma between optimal surgical conditions and the risk of postoperative residual blockade. The aim of the study is to investigate if intense NMB improves surgical conditions during operation in patients scheduled for elective open upper abdominal surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Group STANDARD: Rocuronium 0.6 mg/kg followed by bolus rocuronium according to standard treatment combined with saline infusion (placebo). | |
| DRUG | Group DEEP: Rocuronium 0.6 mg/kg followed by rocuronium infusion with target level PTC 0-1 combined with bolus saline (placebo) mimicking standard treatment. |
Timeline
- Start date
- 2014-09-01
- Primary completion
- 2016-05-01
- Completion
- 2016-06-01
- First posted
- 2014-05-16
- Last updated
- 2017-04-20
- Results posted
- 2017-04-20
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT02140593. Inclusion in this directory is not an endorsement.