Clinical Trials Directory

Trials / Completed

CompletedNCT02139397

Study of Difluoromethylornithine (DFMO) in Combination With Bortezomib for Relapsed or Refractory Neuroblastoma

A Phase I/II Trial of DFMO in Combination With Bortezomib in Patients With Relapsed or Refractory Neuroblastoma

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Giselle Sholler · Academic / Other
Sex
All
Age
21 Years
Healthy volunteers
Not accepted

Summary

The purpose of this research study is to evaluate an investigational drug (DFMO) in combination with bortezomib, for relapsed and refractory neuroblastoma. DFMO is an investigational drug because it has not been approved by the U.S. Food and Drug Administration (FDA). This study will look at the safety and tolerability of DFMO in combination with bortezomib as well as the tumors response to this study drug.

Conditions

Interventions

TypeNameDescription
DRUGDFMO
DRUGBortezomib

Timeline

Start date
2014-06-06
Primary completion
2024-01-19
Completion
2024-01-19
First posted
2014-05-15
Last updated
2024-08-06
Results posted
2024-04-25

Locations

6 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02139397. Inclusion in this directory is not an endorsement.