Trials / Completed
CompletedNCT02133105
Levosimendan Versus Dobutamine for Renal Function in Heart Failure
Efficacy of Intravenous Levosimendan Compared With Dobutamine on Renal Hemodynamics and Function in Chronic Heart Failure
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 33 (actual)
- Sponsor
- Göteborg University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Although inotropes have a favorable effect on central hemodynamics in patients with heart failure, their effect on renal hemodynamics is incompletely defined. The purpose of this study is to evaluate the efficacy of a 75 min intravenous infusion of levosimendan compared to a 75 min infusion of dobutamine on renal hemodynamics and function in patients with chronic heart failure and signs of cardiorenal syndrome. The investigators hypothesis is that patients treated with levosimendan will show greater increases in renal blood flow and glomerular filtration rate (GFR) than those treated with dobutamine.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Levosimendan | |
| DRUG | Dobutamine |
Timeline
- Start date
- 2014-04-01
- Primary completion
- 2017-05-01
- Completion
- 2017-05-01
- First posted
- 2014-05-07
- Last updated
- 2020-02-25
Locations
1 site across 1 country: Sweden
Source: ClinicalTrials.gov record NCT02133105. Inclusion in this directory is not an endorsement.