NCT02131220

Effects of Intracoronary Prourokinase on the Coronary Flow During Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction

A Randomized, Parallel-controlled, Multi-center Study of the Effects of Intracoronary Recombinant HUman Prourokinase or TIrofiban on the Coronary Flow During Primary PCI for the Acute Myocardial InfartiON

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 362 (actual)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether intracoronary selective thrombolysis are more effective than tirofiban on the coronary flow during primary percutaneous coronary intervention for the acute myocardial infarction.

Conditions

• Myocardial Infarction
• Percutaneous Coronary Intervention
• Thrombolytic Therapy

Interventions

Type	Name	Description
DRUG	Prourokinase	20mg intracoronary bolus infusion using selective catheter during PCI
DRUG	Tirofiban	10ug/kg intracoronary bolus infusion using selective catheter during PCI
DRUG	normal saline	intracoronary bolus infusion using selective catheter during PCI

Timeline

• Start date: 2015-11-01
• Primary completion: 2017-08-01
• Completion: 2017-09-01
• First posted: 2014-05-06
• Last updated: 2018-08-07

Locations

1 site across 1 country: China