NCT02128178

Laparoscopic Bariatric Surgery: Two Regimens of Venous Thromboprophylaxis: Prospective Randomized Study

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 700 (estimated)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Obese patients undergoing bariatric surgery warrant VTE prophylaxis because they are at high risk for developing a fatal pulmonary embolism or postthrombotic syndrome. However, a consensus does not exist on the most effective prophylactic approach.

Detailed description

Two regimens of prophylaxis are supposed , the 1st one is to give enoxaparin 40mg 2 hours before surgery and continued daily for 10 days after, and the 2nd one is to start 12 hours before surgery and continued in the same way like the 1st one.

Conditions

• Morbid Obesity
• Pulmonary Embolism

Interventions

Type	Name	Description
DRUG	Enoxaparin 40 mg 2 hours before arm	Enoxaparin 40 mg 2 hours before surgery
DRUG	Enoxaparin 40 mg 12 hours before arm	Enoxaparin 40 mg 12 hours before surgery

Timeline

• Start date: 2013-11-01
• Primary completion: 2016-04-01
• Completion: 2016-05-01
• First posted: 2014-05-01
• Last updated: 2015-04-08

Locations

1 site across 1 country: Egypt