NCT02125383

ParkinStim: Transcranial Direct Current Stimulation for Parkinson's Disease

ParkinStim: Transcranial Direct Current Stimulation for Parkinson's Disease Phase I

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: Great Lakes NeuroTechnologies Inc. · Industry
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the effects of transcranial direct current stimulation (tDCS) on patients with Parkinson's disease during sleep.

Detailed description

The clinical study will follow a counterbalanced crossover design during which subjects will undergo two separate pairs of two-consecutive-overnight sleep studies and receive anodal tDCS (active or sham) to M1. The first sleep study in each pair will acclimate subjects to the sleep laboratory and minimize "first night" effects, thus no tDCS will be applied. The second sleep study in each pair will include active or sham tDCS, presented in a pseudorandom order such that approximately half of the subjects receive active tDCS first while the other half receives sham first. The two pairs of sleep studies will be separated by one to three weeks.

Conditions

• Parkinson's Disease

Interventions

Type	Name	Description
PROCEDURE	Active tDCS	Anodal tDCS will be applied over motor cortex for 20 minutes, three times during the night while the subject sleeps, each separated by 1 hour
PROCEDURE	Sham tDCS	Sham tDCS will be applied over motor cortex for 20 minutes, three times during the night while the subject sleeps, each separated by 1 hour

Timeline

• Start date: 2014-04-01
• Primary completion: 2015-02-01
• Completion: 2015-02-01
• First posted: 2014-04-29
• Last updated: 2015-03-10

Locations

1 site across 1 country: United States