NCT02124200

High Cessation Rates in Smokers Using Personal Vaporizers

High Cessation Rates in Smokers Using Personal Vaporizers: A Prospective 6-month Pilot Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Universita degli Studi di Catania · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

E-cigarettes are proving to be an attractive long-term alternative to conventional cigarettes. Although they may also help smokers to remain abstinent during their quit attempt, recent clinical trials with first generation e-cigarettes have shown only modest quit rates. Second generation devices may result in much higher quit rates. Their efficacy and safety in long-term smoking cessation and/or smoking reduction studies have never been investigated. In this prospective proof-of-concept study we monitored modifications in smoking habits of 50 regular smokers (unwilling to quit) who were asked to switch to a second generation device focusing on smoking reduction and smoking abstinence. Study participants were invited to attend a total of five study visits: at baseline, week-4, week-8, week-12 and week-24. Product usage, number of cigarettes smoked, and exhaled carbon monoxide (eCO) levels were measured at each visit. Smoking reduction and abstinence rates were calculated. Adverse events and participants' opinions of these products were also reviewed.

Conditions

• Tobacco Addiction

Interventions

Type	Name	Description
DEVICE	EGO/CE4, 9mg nicotine

Timeline

• Start date: 2013-01-01
• Primary completion: 2013-11-01
• Completion: 2013-11-01
• First posted: 2014-04-28
• Last updated: 2014-06-10

Locations

1 site across 1 country: Italy