Clinical Trials Directory

Trials / Completed

CompletedNCT02122484

Colchicine in Coronary Artery Bypass Graft (CABG)

Study of Anti-inflammatory Treatment With Colchicine in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery to Reduce Reperfusion Damage

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
60 (actual)
Sponsor
G.Gennimatas General Hospital · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

There is evidence that inflammatory processes may play a key role during surgical myocardial reperfusion. The hypothesis of this study is that colchicine, an anti-inflammatory agent, may lead to reduction in periprocedural infarct size, when administered during elective coronary artery bypass graft surgery.

Conditions

Interventions

TypeNameDescription
DRUGColchicinecolchicine p.os 0.5 mg bid for two days before undergoing elective CABG surgery and eight days after the operation

Timeline

Start date
2013-11-01
Primary completion
2014-06-01
Completion
2014-11-01
First posted
2014-04-24
Last updated
2014-11-11

Locations

1 site across 1 country: Greece

Source: ClinicalTrials.gov record NCT02122484. Inclusion in this directory is not an endorsement.