NCT02120703

Pregabalin Compared to Gabapentin for Pain Control in Lumbar Disc Surgery

Gabapentin vs. Pregabalin for Post Operative Pain in Lumbar Microdiscectomy: a Randomized Controlled Trial.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Aga Khan University · Academic / Other
• Sex: All
• Age: 30 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Pregabalin is claimed to have superior analgesic effect at lower doses and better pharmacological profile as compared to gabapentin esp. in perioperative pain control after major surgeries like intervertebral disc surgery. The investigators found that pregabalin is equivalent to gabapentin for relief of post-operative pain at a lower dose in patients undergoing intervertebral disc surgery.

Conditions

• Intervertebral Disc Prolapse

Interventions

Type	Name	Description
DRUG	Pregabalin	Pregablin 75 mg per oral two times a day
DRUG	Gabapentin	Gabapentin 200 mg twice daily per oral

Timeline

• Start date: 2011-02-01
• Primary completion: 2011-10-01
• Completion: 2011-10-01
• First posted: 2014-04-23
• Last updated: 2014-04-23

Locations

1 site across 1 country: Pakistan