Clinical Trials Directory

Trials / Completed

CompletedNCT02118025

Coronary Bypass Grafting With Minimal Extracorporeal Circulation System Versus Off-pump Coronary Surgery

Prospective Randomized Comparison of Coronary Bypass Grafting With Minimal Extracorporeal Circulation System (MECC) Versus Off-pump Coronary Surgery. New Insights Into Inflammatory Cytokines.

Status
Completed
Phase
Study type
Observational
Enrollment
230 (actual)
Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Academic / Other
Sex
All
Age
18 Years – 90 Years
Healthy volunteers
Not accepted

Summary

The investigators aimed to evaluate the clinical results and the inflammatory response of the minimal extracorporeal circulation system (MECC) Compared with off-pump coronary revascularization (OPCABG). This is a randomized and prospective study in 230 patients with indications for coronary surgery, with 113 patients in the OPCABG group and 117 in the MECC group. The endpoints were the clinical and biochemical results, intra-operative outcomes and the determination of 19 inflammatory circulating markers, 17 of them for the first time analyzed comparing both techniques.

Conditions

Interventions

TypeNameDescription
PROCEDUREOff-pump coronary artery bypass graftPatients operated with the heart beating, without heart arrest.
PROCEDUREMini extracorporeal circulation bypassPatients operated with a modified extracorporeal circulation system

Timeline

Start date
2006-01-01
Primary completion
2008-11-01
Completion
2013-06-01
First posted
2014-04-21
Last updated
2014-04-21

Locations

1 site across 1 country: Spain

Source: ClinicalTrials.gov record NCT02118025. Inclusion in this directory is not an endorsement.